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Integrated proteogenomic approach identifying a protein signature of COPD and a new splice variant of SORBS1

Translation of genomic alterations to protein changes in chronic obstructive pulmonary disease (COPD) is largely unexplored. Using integrated proteomic and RNA sequencing analysis of COPD and control lung tissues, we identified a protein signature in COPD characterised by extracellular matrix change...

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Detalles Bibliográficos
Autores principales: Brandsma, Corry-Anke, Guryev, Victor, Timens, Wim, Ciconelle, Ana, Postma, Dirkje S, Bischoff, Rainer, Johansson, Maria, Ovchinnikova, Ekaterina S, Malm, Johan, Marko-Varga, Gyorgy, Fehniger, Thomas E, van den Berge, Maarten, Horvatovich, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7029225/
https://www.ncbi.nlm.nih.gov/pubmed/31937552
http://dx.doi.org/10.1136/thoraxjnl-2019-213200