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Integrated proteogenomic approach identifying a protein signature of COPD and a new splice variant of SORBS1
Translation of genomic alterations to protein changes in chronic obstructive pulmonary disease (COPD) is largely unexplored. Using integrated proteomic and RNA sequencing analysis of COPD and control lung tissues, we identified a protein signature in COPD characterised by extracellular matrix change...
Autores principales: | Brandsma, Corry-Anke, Guryev, Victor, Timens, Wim, Ciconelle, Ana, Postma, Dirkje S, Bischoff, Rainer, Johansson, Maria, Ovchinnikova, Ekaterina S, Malm, Johan, Marko-Varga, Gyorgy, Fehniger, Thomas E, van den Berge, Maarten, Horvatovich, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7029225/ https://www.ncbi.nlm.nih.gov/pubmed/31937552 http://dx.doi.org/10.1136/thoraxjnl-2019-213200 |
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