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Randomised, double-blind, multicentre, mixed-methods, dose-escalation feasibility trial of mirtazapine for better treatment of severe breathlessness in advanced lung disease (BETTER-B feasibility)

New treatments are required for severe breathlessness in advanced disease. We conducted a randomised feasibility trial of mirtazapine over 28 days in adults with a modified medical research council breathlessness scale score ≥3. Sixty-four patients were randomised (409 screened), achieving our prima...

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Detalles Bibliográficos
Autores principales: Higginson, Irene J, Wilcock, Andrew, Johnson, Miriam J, Bajwah, Sabrina, Lovell, Natasha, Yi, Deokhee, Hart, Simon P, Crosby, Vincent, Poad, Heather, Currow, David, Best, Emma, Brown, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7029228/
https://www.ncbi.nlm.nih.gov/pubmed/31915308
http://dx.doi.org/10.1136/thoraxjnl-2019-213879