Age-Related Intraneuronal Aggregation of Amyloid-β in Endosomes, Mitochondria, Autophagosomes, and Lysosomes

 This work provides new insight into the age-related basis of Alzheimer’s disease (AD), the composition of intraneuronal amyloid (iAβ), and the mechanism of an age-related increase in iAβ in adult AD-model mouse neurons. A new end-specific antibody for Aβ(45) and another for aggregated forms of Aβ p...

Descripción completa

Detalles Bibliográficos
Autores principales: Brewer, Gregory J., Herrera, Robert A., Philipp, Stephan, Sosna, Justyna, Reyes-Ruiz, Jorge Mauricio, Glabe, Charles G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7029321/
https://www.ncbi.nlm.nih.gov/pubmed/31771065
http://dx.doi.org/10.3233/JAD-190835

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7029321/
https://www.ncbi.nlm.nih.gov/pubmed/31771065
http://dx.doi.org/10.3233/JAD-190835

Ejemplares similares