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Spatially Distributed Amyloid-β Reduces Glucose Metabolism in Mild Cognitive Impairment

BACKGROUND: Several positron emission tomography (PET) studies have explored the relationship between amyloid-β (Aβ), glucose metabolism, and the APOE ɛ4 genotype. It has been reported that APOE ɛ4, and not aggregated Aβ, contributes to glucose hypometabolism in pre-clinical stages of Alzheimer’s di...

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Detalles Bibliográficos
Autores principales: Carbonell, Felix, Zijdenbos, Alex P., Bedell, Barry J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7029335/
https://www.ncbi.nlm.nih.gov/pubmed/31796668
http://dx.doi.org/10.3233/JAD-190560