Cargando…

Spatially Distributed Amyloid-β Reduces Glucose Metabolism in Mild Cognitive Impairment

BACKGROUND: Several positron emission tomography (PET) studies have explored the relationship between amyloid-β (Aβ), glucose metabolism, and the APOE ɛ4 genotype. It has been reported that APOE ɛ4, and not aggregated Aβ, contributes to glucose hypometabolism in pre-clinical stages of Alzheimer’s di...

Descripción completa

Detalles Bibliográficos
Autores principales:	Carbonell, Felix, Zijdenbos, Alex P., Bedell, Barry J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	IOS Press 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7029335/ https://www.ncbi.nlm.nih.gov/pubmed/31796668 http://dx.doi.org/10.3233/JAD-190560

Ejemplares similares

β-Amyloid is associated with aberrant metabolic connectivity in subjects with mild cognitive impairment
por: Carbonell, Felix, et al.
Publicado: (2014)

Hierarchical multivariate covariance analysis of metabolic connectivity
por: Carbonell, Felix, et al.
Publicado: (2014)

Left lateralized cerebral glucose metabolism declines in amyloid-β positive persons with mild cognitive impairment
por: Weise, Christopher M., et al.
Publicado: (2018)

Down syndrome: Distribution of brain amyloid in mild cognitive impairment
por: Keator, David B., et al.
Publicado: (2020)

CSF tau and β-amyloid as biomarkers for mild cognitive impairment
por: Hampel, Harald, et al.
Publicado: (2004)

Spatial Distribution and Hierarchical Clustering of β-Amyloid and Glucose Metabolism in Alzheimer’s Disease
por: Zhou, Da-An, et al.
Publicado: (2022)

Practical algorithms for amyloid β probability in subjective or mild cognitive impairment
por: Maserejian, Nancy, et al.
Publicado: (2019)

Effect of APOE ε4 genotype on amyloid‐β, glucose metabolism, and gray matter volume in cognitively normal individuals and amnestic mild cognitive impairment
por: Li, Weihua, et al.
Publicado: (2022)

Longitudinal associations between β-amyloid and cortical thickness in mild cognitive impairment
por: Mak, Elijah, et al.
Publicado: (2023)

Progression to dementia in memory clinic patients with mild cognitive impairment and normal β-amyloid
por: Rosenberg, Anna, et al.
Publicado: (2019)

Association of Modifiable Lifestyle Factors With Cortical Amyloid Burden and Cerebral Glucose Metabolism in Older Adults With Mild Cognitive Impairment
por: Kimura, Noriyuki, et al.
Publicado: (2020)

Regional amyloid correlates of cognitive performance in ageing and mild cognitive impairment
por: Stevens, Daniel A., et al.
Publicado: (2022)

Spatial inhibition of return is impaired in mild cognitive impairment and mild Alzheimer’s disease
por: Jiang, Xiong, et al.
Publicado: (2021)

Qualitative Comparison of Semantic Memory Impairment in Patients with Amnestic Mild Cognitive Impairment Based on β-Amyloid Status
por: Kim, Ji Eun, et al.
Publicado: (2019)

Mild behavioral impairment is associated with β‐amyloid but not tau or neurodegeneration in cognitively intact elderly individuals
por: Lussier, Firoza Z., et al.
Publicado: (2020)

Dissociation between Brain Amyloid Deposition and Metabolism in Early Mild Cognitive Impairment
por: Wu, Liyong, et al.
Publicado: (2012)

Colocalization of cerebral iron with Amyloid beta in Mild Cognitive Impairment
por: van Bergen, J. M. G., et al.
Publicado: (2016)

Communicating mild cognitive impairment diagnoses with and without amyloid imaging
por: Grill, Joshua D., et al.
Publicado: (2017)

Serum levels of proteins involved in amyloid-β clearance are related to cognitive decline and neuroimaging changes in mild cognitive impairment
por: Liu, Shan, et al.
Publicado: (2019)

Spatial Distribution of Cerebral White Matter Lesions Predicts Progression to Mild Cognitive Impairment and Dementia
por: Mortamais, Marion, et al.
Publicado: (2013)

Regional Disconnection in Alzheimer Dementia and Amyloid-Positive Mild Cognitive Impairment: Association Between EEG Functional Connectivity and Brain Glucose Metabolism
por: Smailovic, Una, et al.
Publicado: (2020)

Distinct amyloid distribution patterns in amyloid positive subcortical vascular cognitive impairment
por: Jang, Hyemin, et al.
Publicado: (2018)

β-Amyloid (1–42) Levels in Cerebrospinal Fluid and Cerebral Atrophy in Mild Cognitive Impairment and Alzheimer's Disease
por: Kaiser, Elmar, et al.
Publicado: (2011)

Subjective Sleep Quality in Amnestic Mild Cognitive Impairment Elderly and Its Possible Relationship With Plasma Amyloid-β
por: Liu, Yajing, et al.
Publicado: (2020)

Quantification of Brain β-Amyloid Load in Parkinson's Disease With Mild Cognitive Impairment: A PET/MRI Study
por: Garon, Michela, et al.
Publicado: (2022)

Topographical distribution of Aβ predicts progression to dementia in Aβ positive mild cognitive impairment
por: Pascoal, Tharick A., et al.
Publicado: (2020)

Neuropsychology and neuroimaging profiles of amyloid-positive versus amyloid-negative amnestic mild cognitive impairment patients
por: Tomadesso, Clémence, et al.
Publicado: (2018)

Tract-Based Spatial Statistics: Application to Mild Cognitive Impairment
por: Wai, Yau-Yau, et al.
Publicado: (2014)

Introducing a gatekeeping system for amyloid status assessment in mild cognitive impairment
por: Doering, E., et al.
Publicado: (2022)

(18)F-THK5351 PET Positivity and Longitudinal Changes in Cognitive Function in β-Amyloid-Negative Amnestic Mild Cognitive Impairment
por: Chun, Min Young, et al.
Publicado: (2022)

Impact of Amyloid Pathology in Mild Cognitive Impairment Subjects: The Longitudinal Cognition and Surface Morphometry Data
por: Chang, Hsin-I, et al.
Publicado: (2022)

A Reduced Astrocyte Response to β-Amyloid Plaques in the Ageing Brain Associates with Cognitive Impairment
por: Mathur, Ryan, et al.
Publicado: (2015)

β-Amyloid PET and (123)I-FP-CIT SPECT in Mild Cognitive Impairment at Risk for Lewy Body Dementia
por: Chen, Qin, et al.
Publicado: (2021)

The impact of subthreshold levels of amyloid deposition on conversion to dementia in patients with amyloid-negative amnestic mild cognitive impairment
por: Kim, Hyung-Ji, et al.
Publicado: (2022)

Mild behavioral impairment correlates of cognitive impairments in older adults without dementia: mediation by amyloid pathology
por: Sun, Yan, et al.
Publicado: (2021)

Disrupted Network Topology Contributed to Spatial Navigation Impairment in Patients With Mild Cognitive Impairment
por: Li, Weiping, et al.
Publicado: (2021)

Independent and Interactive Influences of the APOE Genotype and Beta-Amyloid Burden on Cognitive Function in Mild Cognitive Impairment
por: Seo, Eun Hyun, et al.
Publicado: (2016)

Monitoring disease progression in mild cognitive impairment: Associations between atrophy patterns, cognition, APOE and amyloid
por: Falahati, Farshad, et al.
Publicado: (2017)

Association of MRI Indices of Glymphatic System With Amyloid Deposition and Cognition in Mild Cognitive Impairment and Alzheimer Disease
por: Kamagata, Koji, et al.
Publicado: (2022)

(18)F-florbetaben Aβ imaging in mild cognitive impairment
por: Ong, Kevin, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_udpj49av6pe1rc11sn2mvanm4m