Improved Computational Identification of Drug Response Using Optical Measurements of Human Stem Cell Derived Cardiomyocytes in Microphysiological Systems

Cardiomyocytes derived from human induced pluripotent stem cells (hiPSC-CMs) hold great potential for drug screening applications. However, their usefulness is limited by the relative immaturity of the cells’ electrophysiological properties as compared to native cardiomyocytes in the adult human hea...

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Detalles Bibliográficos
Autores principales: Jæger, Karoline Horgmo, Charwat, Verena, Charrez, Bérénice, Finsberg, Henrik, Maleckar, Mary M., Wall, Samuel, Healy, Kevin E., Tveito, Aslak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7029356/
https://www.ncbi.nlm.nih.gov/pubmed/32116671
http://dx.doi.org/10.3389/fphar.2019.01648

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7029356/
https://www.ncbi.nlm.nih.gov/pubmed/32116671
http://dx.doi.org/10.3389/fphar.2019.01648

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