Chromosome Transplantation: A Possible Approach to Treat Human X-linked Disorders

Many human genetic diseases are associated with gross mutations such as aneuploidies, deletions, duplications, or inversions. For these “structural” disorders, conventional gene therapy, based on viral vectors and/or on programmable nuclease-mediated homologous recombination, is still unsatisfactory...

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Detalles Bibliográficos
Autores principales: Paulis, Marianna, Susani, Lucia, Castelli, Alessandra, Suzuki, Teruhiko, Hara, Takahiko, Straniero, Letizia, Duga, Stefano, Strina, Dario, Mantero, Stefano, Caldana, Elena, Sergi, Lucia Sergi, Villa, Anna, Vezzoni, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7029378/
https://www.ncbi.nlm.nih.gov/pubmed/32099849
http://dx.doi.org/10.1016/j.omtm.2020.01.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7029378/
https://www.ncbi.nlm.nih.gov/pubmed/32099849
http://dx.doi.org/10.1016/j.omtm.2020.01.003

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