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Age-, tumor-, and metastatic tissue-associated DNA hypermethylation of a T-box brain 1 locus in human kidney tissue

BACKGROUND: While a considerable number of tumor-specific hypermethylated loci have been identified in renal cell cancer (RCC), DNA methylation of loci showing successive increases in normal, tumoral, and metastatic tissues could point to genes with high relevance both for the process of tumor devel...

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Detalles Bibliográficos
Autores principales: Serth, Jürgen, Peters, Inga, Dubrowinskaja, Natalia, Reese, Christel, Albrecht, Knut, Klintschar, Michael, Lafos, Marcel, Grote, Alexander, Becker, Albert, Hennenlotter, Jörg, Stenzl, Arnulf, Tezval, Hossein, Kuczyk, Markus A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7029553/
https://www.ncbi.nlm.nih.gov/pubmed/32070431
http://dx.doi.org/10.1186/s13148-020-0823-x