Tracking intratumoral heterogeneity in glioblastoma via regularized classification of single-cell RNA-Seq data

BACKGROUND: Understanding cellular and molecular heterogeneity in glioblastoma (GBM), the most common and aggressive primary brain malignancy, is a crucial step towards the development of effective therapies. Besides the inter-patient variability, the presence of multiple cell populations within tum...

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Detalles Bibliográficos
Autores principales: Lopes, Marta B., Vinga, Susana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7029554/
https://www.ncbi.nlm.nih.gov/pubmed/32070274
http://dx.doi.org/10.1186/s12859-020-3390-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7029554/
https://www.ncbi.nlm.nih.gov/pubmed/32070274
http://dx.doi.org/10.1186/s12859-020-3390-4

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