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Protein velocity and acceleration from single-cell multiomics experiments

The simultaneous quantification of protein and RNA makes possible the inference of past, present, and future cell states from single experimental snapshots. To enable such temporal analysis from multimodal single-cell experiments, we introduce an extension of the RNA velocity method that leverages e...

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Detalles Bibliográficos
Autores principales: Gorin, Gennady, Svensson, Valentine, Pachter, Lior
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7029606/
https://www.ncbi.nlm.nih.gov/pubmed/32070398
http://dx.doi.org/10.1186/s13059-020-1945-3