Patient‐specific logic models of signaling pathways from screenings on cancer biopsies to prioritize personalized combination therapies

Mechanistic modeling of signaling pathways mediating patient‐specific response to therapy can help to unveil resistance mechanisms and improve therapeutic strategies. Yet, creating such models for patients, in particular for solid malignancies, is challenging. A major hurdle to build these models is...

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Detalles Bibliográficos
Autores principales: Eduati, Federica, Jaaks, Patricia, Wappler, Jessica, Cramer, Thorsten, Merten, Christoph A, Garnett, Mathew J, Saez‐Rodriguez, Julio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7029724/
https://www.ncbi.nlm.nih.gov/pubmed/32073727
http://dx.doi.org/10.15252/msb.20188664

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7029724/
https://www.ncbi.nlm.nih.gov/pubmed/32073727
http://dx.doi.org/10.15252/msb.20188664

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