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Patient‐specific logic models of signaling pathways from screenings on cancer biopsies to prioritize personalized combination therapies
Mechanistic modeling of signaling pathways mediating patient‐specific response to therapy can help to unveil resistance mechanisms and improve therapeutic strategies. Yet, creating such models for patients, in particular for solid malignancies, is challenging. A major hurdle to build these models is...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7029724/ https://www.ncbi.nlm.nih.gov/pubmed/32073727 http://dx.doi.org/10.15252/msb.20188664 |