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Lumenal calcification and microvasculopathy in fetuin-A-deficient mice lead to multiple organ morbidity

The plasma protein fetuin-A mediates the formation of protein-mineral colloids known as calciprotein particles (CPP)–rapid clearance of these CPP by the reticuloendothelial system prevents errant mineral precipitation and therefore pathological mineralization (calcification). The mutant mouse strain...

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Detalles Bibliográficos
Autores principales: Herrmann, Marietta, Babler, Anne, Moshkova, Irina, Gremse, Felix, Kiessling, Fabian, Kusebauch, Ulrike, Nelea, Valentin, Kramann, Rafael, Moritz, Robert L., McKee, Marc D., Jahnen-Dechent, Willi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7029858/
https://www.ncbi.nlm.nih.gov/pubmed/32074120
http://dx.doi.org/10.1371/journal.pone.0228503