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Lumenal calcification and microvasculopathy in fetuin-A-deficient mice lead to multiple organ morbidity
The plasma protein fetuin-A mediates the formation of protein-mineral colloids known as calciprotein particles (CPP)–rapid clearance of these CPP by the reticuloendothelial system prevents errant mineral precipitation and therefore pathological mineralization (calcification). The mutant mouse strain...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7029858/ https://www.ncbi.nlm.nih.gov/pubmed/32074120 http://dx.doi.org/10.1371/journal.pone.0228503 |