USP27X negatively regulates antiviral signaling by deubiquitinating RIG-I

RIG-I plays important roles in pathogen sensing and activation of antiviral innate immune responses in response to RNA viruses. RIG-I-mediated signaling must be precisely controlled to maintain innate immune signaling homeostasis. Previous studies demonstrated that lysine 63 (K63)-linked polyubiquit...

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Detalles Bibliográficos
Autores principales: Tao, Xinyue, Chu, Bei, Xin, Di, Li, Lin, Sun, Qinmiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7029883/
https://www.ncbi.nlm.nih.gov/pubmed/32027733
http://dx.doi.org/10.1371/journal.ppat.1008293

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7029883/
https://www.ncbi.nlm.nih.gov/pubmed/32027733
http://dx.doi.org/10.1371/journal.ppat.1008293

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