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Spectroscopic and molecular docking studies reveal binding characteristics of nazartinib (EGF816) to human serum albumin
The interactions of novel anti-cancer therapeutic agents with the different plasma and tissue components, specifically serum albumins, have lately gained considerable attention due to the significant influence of such interactions on the pharmacokinetics and/or -dynamics of this important class of t...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7029911/ https://www.ncbi.nlm.nih.gov/pubmed/32218978 http://dx.doi.org/10.1098/rsos.191595 |