Modelling of dysregulated glucagon secretion in type 2 diabetes by considering mitochondrial alterations in pancreatic α-cells

Type 2 diabetes mellitus (T2DM) has been associated with insulin resistance and the failure of β-cells to produce and secrete enough insulin as the disease progresses. However, clinical treatments based solely on insulin secretion and action have had limited success. The focus is therefore shifting...

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Detalles Bibliográficos
Autores principales: Grubelnik, Vladimir, Markovič, Rene, Lipovšek, Saška, Leitinger, Gerd, Gosak, Marko, Dolenšek, Jurij, Valladolid-Acebes, Ismael, Berggren, Per-Olof, Stožer, Andraž, Perc, Matjaž, Marhl, Marko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2020
Materias:
Physics and Biophysics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7029933/
https://www.ncbi.nlm.nih.gov/pubmed/32218947
http://dx.doi.org/10.1098/rsos.191171

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7029933/
https://www.ncbi.nlm.nih.gov/pubmed/32218947
http://dx.doi.org/10.1098/rsos.191171

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