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More stressed out with age? Check your RNA granule aggregation
Low complexity (LC) prion-like domains are over-represented among RNA-binding proteins (RBPs) and contribute to the dynamic nature of RNA granules. Importantly, several neurodegenerative diseases are characterized by cytoplasmic “solid” aggregates formed by mainly nuclear RBPs harboring LC prion-lik...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7030885/ https://www.ncbi.nlm.nih.gov/pubmed/28956717 http://dx.doi.org/10.1080/19336896.2017.1356559 |