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More stressed out with age? Check your RNA granule aggregation

Low complexity (LC) prion-like domains are over-represented among RNA-binding proteins (RBPs) and contribute to the dynamic nature of RNA granules. Importantly, several neurodegenerative diseases are characterized by cytoplasmic “solid” aggregates formed by mainly nuclear RBPs harboring LC prion-lik...

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Detalles Bibliográficos
Autores principales: Lechler, Marie C., David, Della C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7030885/
https://www.ncbi.nlm.nih.gov/pubmed/28956717
http://dx.doi.org/10.1080/19336896.2017.1356559