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The structure of the infectious prion protein: Experimental data and molecular models
The structures of the infectious prion protein, PrP(Sc), and that of its proteolytically truncated variant, PrP 27–30, have evaded experimental determination due to their insolubility and propensity to aggregate. Molecular modeling has been used to fill this void and to predict their structures, but...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7030906/ https://www.ncbi.nlm.nih.gov/pubmed/24583975 http://dx.doi.org/10.4161/pri.28368 |