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LATS kinase–mediated CTCF phosphorylation and selective loss of genomic binding

Chromatin topological organization is instrumental in gene transcription. Gene-enhancer interactions are accommodated in the same CTCF-mediated insulated neighborhoods. However, it remains poorly understood whether and how the 3D genome architecture is dynamically restructured by external signals. H...

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Detalles Bibliográficos
Autores principales: Luo, Huacheng, Yu, Qin, Liu, Yang, Tang, Ming, Liang, Mingwei, Zhang, Dingpeng, Xiao, Tsan Sam, Wu, Lizi, Tan, Ming, Ruan, Yijun, Bungert, Jörg, Lu, Jianrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7030924/
https://www.ncbi.nlm.nih.gov/pubmed/32128389
http://dx.doi.org/10.1126/sciadv.aaw4651