Sensory neuron–derived Na(V)1.7 contributes to dorsal horn neuron excitability

Expression of the voltage-gated sodium channel Na(V)1.7 in sensory neurons is required for pain sensation. We examined the role of Na(V)1.7 in the dorsal horn of the spinal cord using an epitope-tagged Na(V)1.7 knock-in mouse. Immuno–electron microscopy showed the presence of Na(V)1.7 in dendrites o...

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Detalles Bibliográficos
Autores principales: Alles, Sascha R. A., Nascimento, Filipe, Luján, Rafael, Luiz, Ana P., Millet, Queensta, Bangash, M. Ali, Santana-Varela, Sonia, Zhou, Xuelong, Cox, James J., Okorokov, Andrei L., Beato, Marco, Zhao, Jing, Wood, John N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7030926/
https://www.ncbi.nlm.nih.gov/pubmed/32128393
http://dx.doi.org/10.1126/sciadv.aax4568

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7030926/
https://www.ncbi.nlm.nih.gov/pubmed/32128393
http://dx.doi.org/10.1126/sciadv.aax4568

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