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Engineering light-controllable CAR T cells for cancer immunotherapy

T cells engineered to express chimeric antigen receptors (CARs) can recognize and engage with target cancer cells with redirected specificity for cancer immunotherapy. However, there is a lack of ideal CARs for solid tumor antigens, which may lead to severe adverse effects. Here, we developed a ligh...

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Detalles Bibliográficos
Autores principales: Huang, Ziliang, Wu, Yiqian, Allen, Molly E., Pan, Yijia, Kyriakakis, Phillip, Lu, Shaoying, Chang, Ya-Ju, Wang, Xin, Chien, Shu, Wang, Yingxiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7030928/
https://www.ncbi.nlm.nih.gov/pubmed/32128416
http://dx.doi.org/10.1126/sciadv.aay9209