Sustained IFN-I stimulation impairs MAIT cell responses to bacteria by inducing IL-10 during chronic HIV-1 infection

Mucosal-associated invariant T (MAIT) cells in HIV-1–infected individuals are functionally impaired by poorly understood mechanisms. Single-cell transcriptional and surface protein analyses revealed that peripheral MAIT cells from HIV-1–infected subjects were highly activated with the up-regulation...

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Detalles Bibliográficos
Autores principales: Tang, X., Zhang, S., Peng, Q., Ling, L., Shi, H., Liu, Y., Cheng, L., Xu, L., Chakrabarti, L. A., Chen, Z., Wang, H., Zhang, Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7030930/
https://www.ncbi.nlm.nih.gov/pubmed/32128419
http://dx.doi.org/10.1126/sciadv.aaz0374

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7030930/
https://www.ncbi.nlm.nih.gov/pubmed/32128419
http://dx.doi.org/10.1126/sciadv.aaz0374

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