Cargando…

miRNA-31 Improves Cognition and Abolishes Amyloid-β Pathology by Targeting APP and BACE1 in an Animal Model of Alzheimer’s Disease

Alzheimer’s disease (AD) is the most common form of dementia worldwide, characterized by progressive memory impairment, behavioral changes, and, ultimately, loss of consciousness and death. Recently, microRNA (miRNA) dysfunction has been associated with increased production and impaired clearance of...

Descripción completa

Detalles Bibliográficos
Autores principales: Barros-Viegas, Ana Teresa, Carmona, Vítor, Ferreiro, Elisabete, Guedes, Joana, Cardoso, Ana Maria, Cunha, Pedro, Pereira de Almeida, Luís, Resende de Oliveira, Catarina, Pedro de Magalhães, João, Peça, João, Cardoso, Ana Luísa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031139/
https://www.ncbi.nlm.nih.gov/pubmed/32069773
http://dx.doi.org/10.1016/j.omtn.2020.01.010