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miRNA-31 Improves Cognition and Abolishes Amyloid-β Pathology by Targeting APP and BACE1 in an Animal Model of Alzheimer’s Disease
Alzheimer’s disease (AD) is the most common form of dementia worldwide, characterized by progressive memory impairment, behavioral changes, and, ultimately, loss of consciousness and death. Recently, microRNA (miRNA) dysfunction has been associated with increased production and impaired clearance of...
Autores principales: | Barros-Viegas, Ana Teresa, Carmona, Vítor, Ferreiro, Elisabete, Guedes, Joana, Cardoso, Ana Maria, Cunha, Pedro, Pereira de Almeida, Luís, Resende de Oliveira, Catarina, Pedro de Magalhães, João, Peça, João, Cardoso, Ana Luísa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031139/ https://www.ncbi.nlm.nih.gov/pubmed/32069773 http://dx.doi.org/10.1016/j.omtn.2020.01.010 |
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