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Functional loss of inactive rhomboid-like protein 2 mitigates obesity by suppressing pro-inflammatory macrophage activation-triggered adipose inflammation

OBJECTIVE: Chronic inflammation of adipose tissues contributes to obesity-triggered insulin resistance. Unfortunately, the potential molecular mechanisms regarding obesity-associated systemic inflammation and metabolic disorder remain complicated. Here, we report that inactive rhomboid-like protein...

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Detalles Bibliográficos
Autores principales: Xu, Minxuan, Ge, Chenxu, Qin, Yuting, Lou, Deshuai, Li, Qiang, Feng, Jing, Wu, Yekuan, Hu, Linfeng, Wang, Bochu, Tan, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031140/
https://www.ncbi.nlm.nih.gov/pubmed/32180551
http://dx.doi.org/10.1016/j.molmet.2020.01.008