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Functional loss of inactive rhomboid-like protein 2 mitigates obesity by suppressing pro-inflammatory macrophage activation-triggered adipose inflammation
OBJECTIVE: Chronic inflammation of adipose tissues contributes to obesity-triggered insulin resistance. Unfortunately, the potential molecular mechanisms regarding obesity-associated systemic inflammation and metabolic disorder remain complicated. Here, we report that inactive rhomboid-like protein...
Autores principales: | Xu, Minxuan, Ge, Chenxu, Qin, Yuting, Lou, Deshuai, Li, Qiang, Feng, Jing, Wu, Yekuan, Hu, Linfeng, Wang, Bochu, Tan, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031140/ https://www.ncbi.nlm.nih.gov/pubmed/32180551 http://dx.doi.org/10.1016/j.molmet.2020.01.008 |
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