Histone methyltransferases regulate the transcriptional expression of ERα and the proliferation of tamoxifen-resistant breast cancer cells

PURPOSE: Although tamoxifen remains the frontline treatment for ERα-positive breast cancers, resistance to this drug limits its clinical efficacy. Most tamoxifen-resistant patients retain ERα expression which may support growth and progression of breast cancers. Therefore, we investigated epigenetic...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Seung-Su, Lee, Min-Ho, Lee, Mi-Ock
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Preclinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031178/
https://www.ncbi.nlm.nih.gov/pubmed/31897900
http://dx.doi.org/10.1007/s10549-019-05517-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031178/
https://www.ncbi.nlm.nih.gov/pubmed/31897900
http://dx.doi.org/10.1007/s10549-019-05517-0

Ejemplares similares