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Controllability analysis of molecular pathways points to proteins that control the entire interaction network
Inputs to molecular pathways that are the backbone of cellular activity drive the cell to certain outcomes and phenotypes. Here, we investigated proteins that topologically controlled different human pathways represented as independent molecular interaction networks, suggesting that a minority of pr...
Autores principales: | Devkota, Prajwal, Wuchty, Stefan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031241/ https://www.ncbi.nlm.nih.gov/pubmed/32076007 http://dx.doi.org/10.1038/s41598-020-59717-6 |
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