The effect of phage genetic diversity on bacterial resistance evolution

CRISPR-Cas adaptive immune systems are found in bacteria and archaea and provide defence against phage by inserting phage-derived sequences into CRISPR loci on the host genome to provide sequence specific immunological memory against re-infection. Under laboratory conditions the bacterium Pseudomona...

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Detalles Bibliográficos
Autores principales: Broniewski, Jenny M., Meaden, Sean, Paterson, Steve, Buckling, Angus, Westra, Edze R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031251/
https://www.ncbi.nlm.nih.gov/pubmed/31896785
http://dx.doi.org/10.1038/s41396-019-0577-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031251/
https://www.ncbi.nlm.nih.gov/pubmed/31896785
http://dx.doi.org/10.1038/s41396-019-0577-7

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