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Alterations in promoter interaction landscape and transcriptional network underlying metabolic adaptation to diet
Metabolic adaptation to nutritional state requires alterations in gene expression in key tissues. Here, we investigated chromatin interaction dynamics, as well as alterations in cis-regulatory loci and transcriptional network in a mouse model system. Chronic consumption of a diet high in saturated f...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031266/ https://www.ncbi.nlm.nih.gov/pubmed/32075973 http://dx.doi.org/10.1038/s41467-020-14796-x |