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Alterations in promoter interaction landscape and transcriptional network underlying metabolic adaptation to diet

Metabolic adaptation to nutritional state requires alterations in gene expression in key tissues. Here, we investigated chromatin interaction dynamics, as well as alterations in cis-regulatory loci and transcriptional network in a mouse model system. Chronic consumption of a diet high in saturated f...

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Detalles Bibliográficos
Autores principales: Qin, Yufeng, Grimm, Sara A., Roberts, John D., Chrysovergis, Kaliopi, Wade, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031266/
https://www.ncbi.nlm.nih.gov/pubmed/32075973
http://dx.doi.org/10.1038/s41467-020-14796-x