Compensatory mutations modulate the competitiveness and dynamics of plasmid-mediated colistin resistance in Escherichia coli clones

The emergence of mobile colistin resistance (mcr) threatens to undermine the clinical efficacy of the last antibiotic that can be used to treat serious infections caused by Gram-negative pathogens. Here we measure the fitness cost of a newly discovered MCR-3 using in vitro growth and competition ass...

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Detalles Bibliográficos
Autores principales: Yang, Qiu E., MacLean, Craig, Papkou, Andrei, Pritchard, Manon, Powell, Lydia, Thomas, David, Andrey, Diego O., Li, Mei, Spiller, Brad, Yang, Wang, Walsh, Timothy R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031280/
https://www.ncbi.nlm.nih.gov/pubmed/31896787
http://dx.doi.org/10.1038/s41396-019-0578-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031280/
https://www.ncbi.nlm.nih.gov/pubmed/31896787
http://dx.doi.org/10.1038/s41396-019-0578-6

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