Cargando…
Compensatory mutations modulate the competitiveness and dynamics of plasmid-mediated colistin resistance in Escherichia coli clones
The emergence of mobile colistin resistance (mcr) threatens to undermine the clinical efficacy of the last antibiotic that can be used to treat serious infections caused by Gram-negative pathogens. Here we measure the fitness cost of a newly discovered MCR-3 using in vitro growth and competition ass...
Autores principales: | Yang, Qiu E., MacLean, Craig, Papkou, Andrei, Pritchard, Manon, Powell, Lydia, Thomas, David, Andrey, Diego O., Li, Mei, Spiller, Brad, Yang, Wang, Walsh, Timothy R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031280/ https://www.ncbi.nlm.nih.gov/pubmed/31896787 http://dx.doi.org/10.1038/s41396-019-0578-6 |
Ejemplares similares
-
Novel Plasmid-Mediated Colistin Resistance Gene mcr-3 in Escherichia coli
por: Yin, Wenjuan, et al.
Publicado: (2017) -
Positive selection and compensatory adaptation interact to stabilize non-transmissible plasmids
por: Millan, A. San, et al.
Publicado: (2014) -
Balancing mcr-1 expression and bacterial survival is a delicate equilibrium between essential cellular defence mechanisms
por: Yang, Qiue, et al.
Publicado: (2017) -
Off-Target Integron Activity Leads to Rapid Plasmid Compensatory Evolution in Response to Antibiotic Selection Pressure
por: Souque, Célia, et al.
Publicado: (2023) -
Erratum for Yin et al., “Novel Plasmid-Mediated Colistin Resistance Gene mcr-3 in Escherichia coli”
por: Yin, Wenjuan, et al.
Publicado: (2017)