Activated FGF2 signaling pathway in tumor vasculature is essential for acquired resistance to anti-VEGF therapy

Anti–vascular endothelial growth factor (VEGF) therapy shows antitumor activity against various types of solid cancers. Several resistance mechanisms against anti-VEGF therapy have been elucidated; however, little is known about the mechanisms by which the acquired resistance arises. Here, we develo...

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Detalles Bibliográficos
Autores principales: Ichikawa, Kenji, Watanabe Miyano, Saori, Minoshima, Yukinori, Matsui, Junji, Funahashi, Yasuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031295/
https://www.ncbi.nlm.nih.gov/pubmed/32076044
http://dx.doi.org/10.1038/s41598-020-59853-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031295/
https://www.ncbi.nlm.nih.gov/pubmed/32076044
http://dx.doi.org/10.1038/s41598-020-59853-z

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