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Calcineurin Signaling Mediates Disruption of the Axon Initial Segment Cytoskeleton after Injury
The axon initial segment (AIS) cytoskeleton undergoes rapid and irreversible disruption prior to cell death after injury, and loss of AIS integrity can produce profound neurological effects on the nervous system. Here we described a previously unrecognized mechanism for ischemia-induced alterations...
Autores principales: | Zhao, Yanan, Wu, Xuanyuan, Chen, Xin, Li, Jianan, Tian, Cuiping, Chen, Jiangrui, Xiao, Cheng, Zhong, Guisheng, He, Shuijin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031317/ https://www.ncbi.nlm.nih.gov/pubmed/32062456 http://dx.doi.org/10.1016/j.isci.2020.100880 |
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