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The nuclear gene rpl18 regulates erythroid maturation via JAK2-STAT3 signaling in zebrafish model of Diamond–Blackfan anemia

Diamond–Blackfan anemia (DBA) is a rare, inherited bone marrow failure syndrome, characterized by red blood cell aplasia, developmental abnormalities, and enhanced risk of malignancy. However, the underlying pathogenesis of DBA is yet to be understood. Recently, mutations in the gene encoding riboso...

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Detalles Bibliográficos
Autores principales: Chen, Cheng, Lu, Mengjia, Lin, Shuo, Qin, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031319/
https://www.ncbi.nlm.nih.gov/pubmed/32075953
http://dx.doi.org/10.1038/s41419-020-2331-5