NF-κB c-Rel Dictates the Inflammatory Threshold by Acting as a Transcriptional Repressor

NF-κB/Rel family of transcription factors plays a central role in initiation and resolution of inflammatory responses. Here, we identified a function of the NF-κB subunit c-Rel as a transcriptional repressor of inflammatory genes. Genetic deletion of c-Rel substantially potentiates the expression of...

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Detalles Bibliográficos
Autores principales: de Jesús, Tristan James, Ramakrishnan, Parameswaran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031323/
https://www.ncbi.nlm.nih.gov/pubmed/32062419
http://dx.doi.org/10.1016/j.isci.2020.100876

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031323/
https://www.ncbi.nlm.nih.gov/pubmed/32062419
http://dx.doi.org/10.1016/j.isci.2020.100876

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