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NF-κB c-Rel Dictates the Inflammatory Threshold by Acting as a Transcriptional Repressor
NF-κB/Rel family of transcription factors plays a central role in initiation and resolution of inflammatory responses. Here, we identified a function of the NF-κB subunit c-Rel as a transcriptional repressor of inflammatory genes. Genetic deletion of c-Rel substantially potentiates the expression of...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031323/ https://www.ncbi.nlm.nih.gov/pubmed/32062419 http://dx.doi.org/10.1016/j.isci.2020.100876 |