Cellular deconvolution of GTEx tissues powers discovery of disease and cell-type associated regulatory variants

The Genotype-Tissue Expression (GTEx) resource has provided insights into the regulatory impact of genetic variation on gene expression across human tissues; however, thus far has not considered how variation acts at the resolution of the different cell types. Here, using gene expression signatures...

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Detalles Bibliográficos
Autores principales: Donovan, Margaret K. R., D’Antonio-Chronowska, Agnieszka, D’Antonio, Matteo, Frazer, Kelly A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031340/
https://www.ncbi.nlm.nih.gov/pubmed/32075962
http://dx.doi.org/10.1038/s41467-020-14561-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031340/
https://www.ncbi.nlm.nih.gov/pubmed/32075962
http://dx.doi.org/10.1038/s41467-020-14561-0

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