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Gemini quaternary ammonium compound PMT12-BF4 inhibits Candida albicans via regulating iron homeostasis

Quaternary ammonium compounds (QACs) are classified as cationic surfactants, and are known for their biocidal activity. However, their modes of action are thus far not completely understood. In this study, we synthesized a gemini QAC, PMT12-BF4 and found that it exerted unsurpassed broad-spectrum an...

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Detalles Bibliográficos
Autores principales: Hsu, Li-Hang, Kwaśniewska, Dobrawa, Wang, Shih-Cheng, Shen, Tang-Long, Wieczorek, Daria, Chen, Ying-Lien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031538/
https://www.ncbi.nlm.nih.gov/pubmed/32076050
http://dx.doi.org/10.1038/s41598-020-59750-5