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Association of GCK gene DNA methylation with the risk of clopidogrel resistance in acute coronary syndrome patients

BACKGROUNDS: Clopidogrel resistance (CR), which was manifested as the failure of platelet inhibition in clopidogrel treatment, was likely to lead to cardiovascular events. Our study was aimed to explore the contribution of DNA methylation in glucokinase (GCK) to the CR risk. METHODS: Among 36 CR and...

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Detalles Bibliográficos
Autores principales: Su, Jia, Zheng, Nan, Li, Zhenwei, Huangfu, Ning, Mei, Li, Xu, Xiaolei, Zhang, Li, Chen, Xiaomin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031555/
https://www.ncbi.nlm.nih.gov/pubmed/31605429
http://dx.doi.org/10.1002/jcla.23040