Stem cell‐derived retinal pigment epithelium from patients with age‐related macular degeneration exhibit reduced metabolism and matrix interactions

Modeling age‐related macular degeneration (AMD) is challenging, because it is a multifactorial disease. To focus on interactions between the retinal pigment epithelium (RPE) and Bruch's membrane, we generated RPE from AMD patients and used an altered extracellular matrix (ECM) that models aged...

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Detalles Bibliográficos
Autores principales: Gong, Jie, Cai, Hui, Noggle, Scott, Paull, Daniel, Rizzolo, Lawrence J., Del Priore, Lucian V., Fields, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Pluripotent Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031648/
https://www.ncbi.nlm.nih.gov/pubmed/31840941
http://dx.doi.org/10.1002/sctm.19-0321

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031648/
https://www.ncbi.nlm.nih.gov/pubmed/31840941
http://dx.doi.org/10.1002/sctm.19-0321

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