Computational Modeling Reveals Frequency Modulation of Calcium-cAMP/PKA Pathway in Dendritic Spines

Dendritic spines are the primary excitatory postsynaptic sites that act as subcompartments of signaling. Ca(2+) is often the first and most rapid signal in spines. Downstream of calcium, the cyclic adenosine monophosphate (cAMP)/protein kinase A (PKA) pathway plays a critical role in the regulation...

Descripción completa

Detalles Bibliográficos
Autores principales: Ohadi, Donya, Schmitt, Danielle L., Calabrese, Barbara, Halpain, Shelley, Zhang, Jin, Rangamani, Padmini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031750/
https://www.ncbi.nlm.nih.gov/pubmed/31668749
http://dx.doi.org/10.1016/j.bpj.2019.10.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031750/
https://www.ncbi.nlm.nih.gov/pubmed/31668749
http://dx.doi.org/10.1016/j.bpj.2019.10.003

Ejemplares similares