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Computational Modeling Reveals Frequency Modulation of Calcium-cAMP/PKA Pathway in Dendritic Spines
Dendritic spines are the primary excitatory postsynaptic sites that act as subcompartments of signaling. Ca(2+) is often the first and most rapid signal in spines. Downstream of calcium, the cyclic adenosine monophosphate (cAMP)/protein kinase A (PKA) pathway plays a critical role in the regulation...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Biophysical Society
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031750/ https://www.ncbi.nlm.nih.gov/pubmed/31668749 http://dx.doi.org/10.1016/j.bpj.2019.10.003 |