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Subtype-specific transcriptional regulators in breast tumors subjected to genetic and epigenetic alterations

MOTIVATION: Breast cancer consists of multiple distinct tumor subtypes, and results from epigenetic and genetic aberrations that give rise to distinct transcriptional profiles. Despite previous efforts to understand transcriptional deregulation through transcription factor networks, the transcriptio...

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Detalles Bibliográficos
Autores principales: Zhu, Qian, Tekpli, Xavier, Troyanskaya, Olga G, Kristensen, Vessela N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031777/
https://www.ncbi.nlm.nih.gov/pubmed/31529022
http://dx.doi.org/10.1093/bioinformatics/btz709