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Magainin 2 and PGLa in Bacterial Membrane Mimics I: Peptide-Peptide and Lipid-Peptide Interactions

We addressed the onset of synergistic activity of the two well-studied antimicrobial peptides magainin 2 (MG2a) and PGLa using lipid-only mimics of Gram-negative cytoplasmic membranes. Specifically, we coupled a joint analysis of small-angle x-ray and neutron scattering experiments on fully hydrated...

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Detalles Bibliográficos
Autores principales: Pachler, Michael, Kabelka, Ivo, Appavou, Marie-Sousai, Lohner, Karl, Vácha, Robert, Pabst, Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031808/
https://www.ncbi.nlm.nih.gov/pubmed/31703802
http://dx.doi.org/10.1016/j.bpj.2019.10.022