Hsc70 Ameliorates the Vesicle Recycling Defects Caused by Excess α-Synuclein at Synapses

α-Synuclein overexpression and aggregation are linked to Parkinson’s disease (PD), dementia with Lewy bodies (DLB), and several other neurodegenerative disorders. In addition to effects in the cell body, α-synuclein accumulation occurs at presynapses where the protein is normally localized. While it...

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Detalles Bibliográficos
Autores principales: Banks, Susan M. L., Medeiros, Audrey T., McQuillan, Molly, Busch, David J., Ibarraran-Viniegra, Ana Sofia, Sousa, Rui, Lafer, Eileen M., Morgan, Jennifer R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2020
Materias:
New Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031854/
https://www.ncbi.nlm.nih.gov/pubmed/31941659
http://dx.doi.org/10.1523/ENEURO.0448-19.2020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031854/
https://www.ncbi.nlm.nih.gov/pubmed/31941659
http://dx.doi.org/10.1523/ENEURO.0448-19.2020

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