Polyphyllin VII attenuated RANKL-induced osteoclast differentiation via inhibiting of TRAF6/c-Src/PI3K pathway and ROS production

BACKGROUND: Osteoporosis is a worldwide severe bone disease. This study aimed to evaluate the effect of polyphyllin VII on the genesis of osteoclasts from bone marrow macrophages (BMMs) and its potentiality as a therapeutic drug for osteoporosis. METHODS: BMMs were induced to differentiate into oste...

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Detalles Bibliográficos
Autores principales: Zhou, Long, Song, Hanyi, Zhang, Yiqi, Ren, Zhaozhou, Li, Minghe, Fu, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031869/
https://www.ncbi.nlm.nih.gov/pubmed/32075617
http://dx.doi.org/10.1186/s12891-020-3077-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031869/
https://www.ncbi.nlm.nih.gov/pubmed/32075617
http://dx.doi.org/10.1186/s12891-020-3077-z

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