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A chromosomal connectome for psychiatric and metabolic risk variants in adult dopaminergic neurons
BACKGROUND: Midbrain dopaminergic neurons (MDN) represent 0.0005% of the brain’s neuronal population and mediate cognition, food intake, and metabolism. MDN are also posited to underlay the neurobiological dysfunction of schizophrenia (SCZ), a severe neuropsychiatric disorder that is characterized b...
Autores principales: | Espeso-Gil, Sergio, Halene, Tobias, Bendl, Jaroslav, Kassim, Bibi, Ben Hutta, Gabriella, Iskhakova, Marina, Shokrian, Neda, Auluck, Pavan, Javidfar, Behnam, Rajarajan, Prashanth, Chandrasekaran, Sandhya, Peter, Cyril J., Cote, Alanna, Birnbaum, Rebecca, Liao, Will, Borrman, Tyler, Wiseman, Jennifer, Bell, Aaron, Bannon, Michael J., Roussos, Panagiotis, Crary, John F., Weng, Zhiping, Marenco, Stefano, Lipska, Barbara, Tsankova, Nadejda M., Huckins, Laura, Jiang, Yan, Akbarian, Schahram |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031924/ https://www.ncbi.nlm.nih.gov/pubmed/32075678 http://dx.doi.org/10.1186/s13073-020-0715-x |
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