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Establishment and characterization of patient-derived cancer models of malignant peripheral nerve sheath tumors

BACKGROUND: Malignant peripheral nerve sheath tumors (MPNSTs) are a rare subtype of soft-tissue sarcoma, derived from a peripheral branch or the sheath of the sciatic nerve, brachial plexus, or sacral plexus. The clinical outcomes for MPNST patients with unresectable or metastatic tumors are dismal,...

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Detalles Bibliográficos
Autores principales: Oyama, Rieko, Kito, Fusako, Takahashi, Mami, Hattori, Emi, Noguchi, Rei, Takai, Yoko, Sakumoto, Marimu, Qiao, Zhiwei, Toki, Shunichi, Sugawara, Masato, Tanzawa, Yoshikazu, Kobayashi, Eisuke, Nakatani, Fumihiko, Iwata, Shintaro, Yoshida, Akihiko, Kawai, Akira, Kondo, Tadashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031935/
https://www.ncbi.nlm.nih.gov/pubmed/32099531
http://dx.doi.org/10.1186/s12935-020-1128-z